THE LATEST NEWS: OCTOBER 2017

WELCOME HARRY GENANT

Harry K. Genant, MD, is Professor Emeritus of the University of California San Francisco. Dr. Genant currently serves as a Senior Consultant, and past Member of the Board of Directors and Chairman Emeritus of BioClinica-Synarc, Inc., a global contract research organization he co-founded in 1998. BioClinica-Synarc specializes in the management of quantitative imaging and bio markers in large multicenter, multinational pharmaceutical drug trials.
During his 30+ years at UCSF, Dr. Genant was Professor of Radiology, Medicine, and Orthopedic Surgery, and former Chief of Musculoskeletal Radiology. He also founded the Osteoporosis and Arthritis Research Group, comprising over 130 physicians, scientists and research associates, and was recognized as a leading source of research on the development and assessment of noninvasive and quantitative imaging methods for osteoporosis, arthritis and orthopedics.
Originally from Riverside, Illinois, Dr. Genant received his undergraduate and medical degrees from Northwestern University, and completed his medical internship on the Osler Service at Johns Hopkins University in Baltimore, Maryland. He received residency training in Medicine and in Radiology at the University of Chicago, and was Chief Resident and Assistant Professor in Radiology.
Dr. Genant has made extensive contributions to peer-reviewed scientific and medical journals as author or co-author of over 600 articles and through his membership of the editorial boards of Osteoporosis International, the Journal of Bone, and Mineral Research, and the Journal of Clinical Densitometry and as Associate Editor of Bone.
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Surgery During the 2017 Harvest:

An uncommon story on the power of ultrasound

Michael Wolf, owner of Michael Wolf Vineyard Services and long-time Napa Valley grape producer, suffered for years from Carpal Tunnel Syndrome in both wrists.
Like the 12 million other Americans with this condition, Mike was experiencing numbness, tingling, and weakness in his fingers accompanied by a great deal of discomfort. Eventually he began to lose the ability to grip objects tightly. At night, he would try to sleep in an upright position with his arms hanging loosely at his sides, to minimize the pain. After 35 years of pruning vines, cutting grapes, and digging soil, he was no longer able to fully utilize the tools of his trade, his hands.
With two visits to Dr. Marko Bodor for an ultrasound-guided release procedure – one for each wrist – Mike regained full function of his fingers and hands; years of pain and suffering were simply gone. For the 500,00 traditional carpal tunnel surgeries that take place each year, the experience is entirely different.

In response: The British Journal of Sports and Exercise Medicine

The British Medical Journal Open Sports & Exercise Medicine recently published an article titled, “Normal platelet function in platelet concentrates requires non-platelet cells: a comparative in vitro evaluation of leukocyte-rich (type 1a) and leukocyte-poor (type 3b) platelet concentrates”.
Based on the outcomes of a study designed to evaluate the cellular components of platelet rich plasma (PRP), the authors claimed that leukocyte-rich PRP was superior to leukocyte-poor PRP when supporting the promotion of growth factor release and stimulation of tendon cell proliferation.
Leukocytes are white blood cells, a non-platelet component of platelet-rich plasma. There is current debate across the scientific and medical communities as to the role they play in platelet rich plasma treatments.
Dr. Marko Bodor, Ryan Dregalla, PhD and Yvette Uribe, BS read the article carefully and with great interest, given the current work they are doing in both clinical studies involving the delivery of PRP treatments and in laboratory research investigating PRP on a cellular level. They found inconsistencies in the authors’ preparation and use of the PRP within the study. The authors of the article did not actually use live PRP, but had frozen the platelets and used their extracts to stimulate growth factor release for the tendon cells.

FROM THE RESEARCH LAB:

Mesenchymal Stem Cells

The new laboratory in Suite 2C is already producing meaningful results that increase our understanding of the cellular activity in Platelet-rich plasma (PRP). The NMRF research team is tracking how mesenchymal stem cells (MSCs), leukocytes (white blood cells) and platelets localize with respect to one another through an in vitro disc study. The purpose of the study is to investigate how these cells respond to a damaged disc, and allow us to better determine how to handle intradiscal injections clinically.
MSC cultures are prepared and treated with a viral entity that provides for color differentiation when viewed with a fluorescent microscope. When the cells release a protein, it turns red thus allowing the researches to track it independently of the MSCs and leukocytes. These proteins are routinely tested to identify their response to an extracellular matrix that represents the damaged disc. The platelets are treated with a metabolic dye rendering them green so they, too, are clearly visually identified. Using a flow cytometer, MSC population changes are also observed, indicating if they are surviving and proliferating in the given environment.
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INTRODUCING MICHELLE VOSS

Ms. Voss is a hospitality specialist, with a passion for philanthropy and extensive professional and personal experience in the healing arts. She served as Patron Service Coordinator for Festival Napa Valley, a non-profit organization enriching arts, education and community programs for the Napa Valley. Her responsibilities included sales, database management, vendor coordination, marketing distribution, and donor stewardship. Michelle has also worked in the wine and hospitality industries, enriching her knowledge about Napa Valley wines and deepening her experience in sales and customer service.
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RECENT PRESENTATIONS + LECTURES

 

 

 

Dr. Bodor was delighted to have the opportunity to speak to the Noon Rotary Club of Napa. Thanks to an introduction made by long-time Napa resident and former Rotary President, Dorothy Salmon, the NMRF was able to share news of their progress in developing less invasive, less costly treatments with the lunchtime attendees and their guests.

 

The world’s largest gathering of iphysiatrists took place in Denver, Colorado the week of October 12th. Dr. Bodor joined colleagues from around the globe to discuss innovations in ultrasound, advancements with stem cell therapies, opioid management and the treatment of musculoskeletal pain management, and other similar topics.

A Letter From Our President

A sincere thank you to the Napa Medical Research Foundation’s Board of Directors, staff and our supportive community for allowing me the opportunity to lead the Foundation and promote our important work in regenerative orthopedics research. I am thrilled to get...

Dr. Harry K. Genant: IOF Medal of Achievement

The IOF Medal of AchievementThe International Osteoporosis Foundation (IOF) Medal of Achievement award recognizes a distinguished researcher whose innovative work in the field of non-invasive and quantitative imaging of bone has advanced knowledge in the mechanisms of...

Improving ACL Treatment

ACL Technique Validation Study We asked Dr. Tracy Høeg about the ACL Technique Validation Study to find out what's going on, why this is so important and what she's most excited about! Pictured: Tracy Høeg, MD, PhD   What is the purpose of the ACL Technique...

Spring 2019 Newsletter

The Foundation welcomes Sarah Pursell In April 2019, Sarah Pursell joined our team as the President of the Napa Medical Research Foundation. In this capacity, she will serve as the primary liaison with the Board of Directors and have direct operating responsibility...

Ultrasound-Guided Carpal Tunnel Release Provides Relief

"These are among the happiest patients in my practice. They are appreciative of the almost immediate resolution of pain and numbness at night, and the fast ability to return to work and activities of daily living.” - Dr. Marko Bodor Carpal tunnel syndrome is the most...

An Active Life Restored

Liz H.: A Story of Gratitude "Pain no longer dominates my every minute." "It's hard to express the gratitude in appropriate measure when vitality is returned, and an active life is restored." - Liz H. For 10 years, Liz H. had been trying to find pain relief, and...

Teaming Up with UC Davis for Kids

Oliver Starr has been featured as one of our success stories. Here's how his recovery could help kids with ACL injuries. Extreme Athlete, Extreme recoveryIn March 2018, Oliver's MRI showed his ACL as "nearly normal" after receiving BMAC injections from Dr. Bodor,...

A Letter From Our Founder

As we approach the fifth anniversary of establishing the Napa Medical Research Foundation, we realize how far we have advanced regenerative orthopedics in a short period of time, and we would like to take this opportunity to reflect on how it all got started.  I was...

Winter 2019 Newsletter

A message from our founder Michael and Pepper Jackson with Dr Marko Bodor and his wife, Jackie. As we approach the fifth anniversary of establishing the Napa Medical Research Foundation, we realize how far we have advanced regenerative orthopedics in a short period of...

The Latest News, November 2018

WELCOME GRETCHEN DE BAUBIGNY The NMRF Board of Directors and Staff welcome Gretchen De Baubigny, a resident of St. Helena and San Francisco broadly respected for her creativity, warmth, and lifelong belief in the power of philanthropy. She is an advocate for issues...

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 Reduce Pain. Increase Mobility & Function. Improve Quality of Life.

All the research conducted through the Napa Medical Research Foundation, a 501(c)(3) nonprofit organization, is fully funded through generous donations received from individuals and family foundations.

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